What is Generic Mevacor (Lovastatin)?
Generic Mevacor (Lovastatin) blocks the body's ability to make cholesterol. Generic Mevacor (Lovastatin) can help lower blood cholesterol for patients who are at risk of getting heart disease or a stroke. It is only for patients whose cholesterol level is not controlled by diet. It is not a cure.
What Is Generic Mevacor (Lovastatin) Used For?
Generic Mevacor (Lovastatin) is used, along with diet, to lower cholesterol levels in people with primary hypercholesterolemia (too much cholesterol in the bloodstream). High cholesterol levels foster the buildup of artery-clogging plaque, which can be especially dangerous when it collects in the vessels serving the muscles of the heart. Generic Mevacor (Lovastatin) is prescribed to prevent this problem--called coronary heart disease- -or to slow its advance if the arteries are already clogging up.
!!! Generic Mevacor (Lovastatin) is usually prescribed only if diet, exercise, and weight-loss fail to bring your cholesterol levels under control. It's important to remember that Generic Mevacor (Lovastatin) is a supplement--not a substitute--for these other measures. To get the full benefit of the medication, you need to stick to the diet and exercise program prescribed by your doctor.
Generic Mevacor (Lovastatin) Facts
Active Ingredient: Lovastatin
Inactive Ingredients: inactive ingredients: cellulose, lactose, magnesium stearate, and starch. Butylated hydroxyanisole (BHA) is added as a preservative. Tablets MEVACOR 20 mg also contain FD&C Blue 2.
Class and Mechanism:
Generic Mevacor (Lovastatin) is a cholesterol- lowering medicine. It inhibits the production of cholesterol by the liver. It lowers overall blood cholesterol as well as blood LDL cholesterol levels. LDL cholesterol is believed to be the "bad" cholesterol that is primarily responsible for the development of coronary artery disease. Lowering LDL cholesterol levels retards progression and may even reverse coronary artery disease.
Generic Mevacor (Lovastatin) Storage
Store at room temperature between between 5 and 30 degrees C (41 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date.
How to take Generic Mevacor (Lovastatin)?
May be taken on an empty or full stomach. The medication seems to be most effective when given with the evening meal. Swallow the tablets with a drink of water. Do not take Generic Mevacor (Lovastatin) with grapefruit juice; orange juice may be used instead. Take your doses at regular intervals. Do not take your medicine more often than directed.
The recommended starting dose is 20 milligrams once a day, taken with the evening meal. Your doctor may start you at 10 milligrams a day if you need only a small reduction in cholesterol. The maximum recommended dose is 80 milligrams per day, taken as a single dose or divided into smaller doses, as determined by your doctor. Adjustments to any dose, as determined by your doctor, should be made at intervals of 4 weeks or more.
Cholesterol levels should be monitored periodically by your doctor, who may decide to reduce the dose if your cholesterol level falls below the targeted range.
If you have reduced kidney function, your doctor will be cautious about increasing your dosage.
!!! CHILDREN 10 TO 17 YEARS OLD:
The recommended dosage is 10 to 40 milligrams per day, taken with meals. Adjustments to any dose, as determined by the doctor, should be made at intervals of 4 weeks or more. Girls must have been menstruating for at least 1 year before starting therapy with Generic Mevacor (Lovastatin).
The safety and effectiveness of Generic Mevacor (Lovastatin) in children under 10 years old or in doses greater than 40 milligrams a day have not been studied.
If OVERDOSE
There have been no reported cases of overdose with Generic Mevacor (Lovastatin). However, if you suspect an overdose, seek medical attention immediately.
What to do if I miss a dose?
Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule.
!!! Do not take 2 doses at the same time.
Who should not take Generic Mevacor (Lovastatin)?
If you are being treated for any disease that contributes to increased blood cholesterol, such as hypothyroidism, diabetes, nephritic syndrome (kidney and blood vessel disorder), dysproteinemia (an excess of protein in the blood), or liver disease, your doctor will closely monitor your reaction to Generic Mevacor (Lovastatin).
Drugs like Generic Mevacor (Lovastatin) have occasionally been known to damage muscle tissue, so be sure to tell your doctor immediately if you notice any unexplained muscle tenderness, weakness, or pain, especially if you also have a fever or feel sick. Your doctor may want to do a blood test to check for signs of muscle damage.
It is recommended that liver function tests be performed by your doctor before treatment with Generic Mevacor (Lovastatin) begins, at 6 and 12 weeks after your treatment has started or your dosage has been raised, and periodically (about 6-month intervals) thereafter.
If you are planning to have elective surgery, Generic Mevacor (Lovastatin) should be discontinued a few days before the operation. This drug should be used with caution if you consume substantial quantities of alcohol or have a past history of liver disease.
If you are sensitive to or have ever had an allergic reaction to Generic Mevacor (Lovastatin) or similar anticholesterol drugs, you should not take this medication. Make sure that your doctor is aware of any drug reactions that you have experienced. Unless you are directed to do so by your doctor, do not take this medication if you are being treated for liver disease.
!!! Do not take this drug if you are pregnant or nursing.
What side effects may occur?
Generic Mevacor (Lovastatin) is generally well tolerated. Any side effects that have occurred have usually been mild and short-lived. If any side effects develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Generic Mevacor (Lovastatin).
!!! Side effects may include:
Abdominal pain/cramps, altered sense of taste, blurred vision, constipation, diarrhea, dizziness, gas, headache, heartburn, indigestion, itching, muscle cramps, muscle pain, muscle weakness with rash, nausea, rash, weakness
Generic Mevacor (Lovastatin) Drug Interactions
Generic Mevacor (Lovastatin) tends to enhance the blood-thinning effect of Coumadin. In rare instances, it can also cause muscle pain and potential kidney damage when combined with the following:
- Amiodarone (Cordarone)
- Clarithromycin (Biaxin)
- Clofibrate (Atromid-S)
- Cyclosporine (Sandimmune, Neoral)
- Erythromycin (E.E.S., PCE, others)
- Fenofibrate (Tricor)
- Fluconazole (DiFlucan)
- Gemfibrozil (Lopid)
- Itraconazole (Sporanox)
- Ketoconazole (Nizoral)
- Nefazodone (Serzone)
- Nicotinic acid or niacin (Niaspan)
- Protease inhibitors (a type of drug for HIV) such as Agenerase, Crixivan, Fortovase, Invirase, Norvir, and Viracept
- Verapamil (Calan)
If you are taking Generic Mevacor (Lovastatin) with any of these drugs, (or with large quantities of grapefruit juice), alert your doctor immediately at the first sign of muscle pain, tenderness, or weakness, especially if accompanied by fever or general body discomfort. If you need to take erythromycin, Biaxin, Nizoral, or Sporanox, the doctor may temporarily take you off Generic Mevacor (Lovastatin).
Additional Information
Keep out of the reach of children in a container that small children cannot open.