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Generic Imitrex (Sumatriptan) is the first of a class of medications commonly referred to as the "triptans". It is a specific medication for aborting migraine headaches. It is also effective in cluster headache as an abortive medication.

Generic Imitrex (Sumatriptan) is prescribed for the treatment of a migraine attack with or without the presence of an aura (visual disturbances, usually sensations of halos or flickering lights, which precede an attack). Generic Imitrex (Sumatriptan) cuts headaches short. It will not reduce the number of attacks you experience.

Active Ingredients: Sumatriptan
Other Ingredients: croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, microcrystalline cellulose, and sodium bicarbonate. Each 100-mg tablet also contains hypromellose, iron oxide, titanium dioxide, and triacetin.
Class and Mechanism: Sumatriptan is an antimigraine medicine. Migraine headaches are believed to result from dilatation of the blood vessels in the head. Sumatriptan causes constriction of the blood vessels, thus relieving migraine headache. While it is very effective in relieving migraine, it does not prevent or reduce the number of attacks of migraine.

Keep out of the reach of children in a container that small children cannot open. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date.

Take Generic Imitrex (Sumatriptan) tablets by mouth. Follow the directions on the prescription label. Generic Imitrex (Sumatriptan) is taken at the first symptoms of a migraine attack; it is not for everyday use. Swallow the tablets with a drink of water. If your migraine headache returns after one dose, you can take another dose as directed. You must leave at least 2 hours between doses, and do not take more than 100 mg as a single dose. Do not take more than 200 mg total in any 24 hour period. If there is no improvement at all after the first dose, do not take a second dose without talking to your prescriber or health care professional. Do not take your medicine more often than directed. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. When OVERDOSE is suspected contact either your doctor, hospital emergency department, or nearest poison control center immediately.

Since Generic Imitrex (Sumatriptan) is used to treat migraines or cluster headaches as they occur and not to prevent them, missing a dose is not a problem. Use only the doses you need, according to your doctor's instructions.

You should not take Generic Imitrex (Sumatriptan) if you have (or have had) any of following conditions:
• uncontrolled high blood pressure
• heart disease or a history of heart disease
• hemiplegic or basilar migraine (if you are not sure about this, ask your healthcare professional)
• stroke
• have circulation (blood flow) problems to your arms, legs, and bowels
• have taken another migraine medicine in the same drug class as Generic Imitrex (Sumatriptan) or other migraine medicines that contain ergotamine, dihydroergotamine, or methylsergide in the last 24 hours (ask your healthcare professional for a list of these medicines if you are unsure)
• take a monoamine oxidase (MAO) inhibitor medicine or have taken a MAO inhibitor in the past 2 weeks
• severe liver disease

If you experience any of the following serious side effects, stop using imitrex and seek emergency medical attention:
• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
• severe or prolonged chest pain or an irregular heartbeat;
• chest, jaw, or neck pain or tightness;
• sudden or severe stomach pain;
• problems seeing; or
• unusual weakness or numbness.

Other, less serious side effects may be more likely to occur. Continue to use imitrex and talk to your doctor if you experience
• nausea;
• drowsiness or dizziness;
• tingling, flushing, warmth, redness, or heaviness of a body part;
• unpleasant taste in the mouth (nasal spray);
• nasal irritation (nasal spray); or
• njection site discomfort (injection).

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

If Generic Imitrex (Sumatriptan) is taken with certain other drugs, the effects of either may be increased, decreased, or altered. It is important to check with your doctor before combining Generic Imitrex (Sumatriptan) with the following: Drugs classified as MAO inhibitors, including the antidepressants Nardil and Parnate Ergot-containing drugs such as Cafergot and Ergostat Fluoxetine (Prozac) Fluvoxamine (Luvox) Paroxetine (Paxil) Sertraline (Zoloft)

Do not drive, use machinery, or do anything that needs mental alertness until you know how Generic Imitrex (Sumatriptan) affects you. To reduce dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can increase drowsiness, dizziness and flushing. Avoid alcoholic drinks. Smoking cigarettes may increase the risk of heart-related side effects from using Generic Imitrex (Sumatriptan).